Semaglutide vs Tirzepatide
Two peptides people compare often—different categories, different label contexts. Read each profile before mixing routines or protocols.
Semaglutide
GLP-1 agonist
A GLP-1 receptor agonist peptide drug approved for type 2 diabetes and chronic weight management.
Semaglutide mimics glucagon-like peptide-1, slowing gastric emptying and increasing satiety. Weekly injection versions (Ozempic, Wegovy) produce significant weight loss in trials. It is a prescription drug—not a supple…
Tirzepatide
GLP-1 / GIP agonist
A dual GIP and GLP-1 receptor agonist with strong weight-loss and glycemic data in trials.
Tirzepatide activates both GLP-1 and GIP receptors—a newer mechanism than semaglutide alone. SURMOUNT trials showed ~20% body weight loss at higher doses. Prescription-only; side effects include nausea and rare pancrea…
Quick comparison
- Semaglutide: GLP-1 agonist — A GLP-1 receptor agonist peptide drug approved for type 2 diabetes and chronic weight management.…
- Tirzepatide: GLP-1 / GIP agonist — A dual GIP and GLP-1 receptor agonist with strong weight-loss and glycemic data in trials.…